Your body uses nutrients from healthy foods to heal wounds caused by injury, surgery, or pressure injuries. One of the most important functions of vitamin C is its ability to stimulate the … USA.gov. Perucca Orfei C, Viganò M, Pearson JR, Colombini A, De Luca P, Ragni E, Santos-Ruiz L, de Girolamo L. Int J Mol Sci. Citrus fruits and leafy green vegetables are great sources of vitamin C. The average adult on a 2000 kcal diet was required to get at least 60 mg of vitamin C a day to prevent a deficiency and associated side effects. 1996;25:249-64. doi: 10.1007/978-1-4613-0325-1_13. Free radicals might play a role in heart disease, cancer and other diseases. Please Support My Work With a PayPal Donation. There is an association between vitamin C deficiency and the loss of important skin functions. This site needs JavaScript to work properly. Deficiencies affect the maturation phase by altering collagen production and scar formation. Although inflammation is needed during the first phases of the wound healing process, at a certain point during this process it has to subside in order to allow proper skin tissue regeneration and vascularization. The vitamin is taken up by white blood cells (examples: mast cells, macrophages) and is present in tissues, organs and systems throughout the body, including skin cells, tendons, ligaments, cartilage, blood plasma and bone tissue. Eur Surg Res. 2) Inflammation: Caused by white blood cells infiltrating the site of the wound to clear out pathogens and prevent infection. Clinical studies provide evidence that wound healing in subjects judged not deficient in vitamin C can be significantly accelerated with supplements of this nutrient above the recommended daily allowance (RDA). Neutrophils eat bacteria or other pathogens. 2016 Jul 11;4(7):e792. 2019 Jan 3;20(1):149. doi: 10.3390/ijms20010149. Monocytes turn into macrophages which also digest any existing pathogens. The recommended daily intake has recently been risen to 75 mg of vitamin C a day for women and 90 mg for men. Relationships between tensile strength, ascorbic acid, hydroxyproline, and zinc levels of rabbit full-thickness incision wound healing. There are several functions of the vitamin that contribute to a faster wound healing time and other skin benefits: 1) Collagen synthesis. Let the greats be given their due. Wounds can get infected at any stage during the healing process. Vitamin C also strengthens blood vessel walls. Ascorbic acid, also known as vitamin C, is necessary for wound healing. In Vitro Induction of Tendon-Specific Markers in Tendon Cells, Adipose- and Bone Marrow-Derived Stem Cells is Dependent on TGFβ3, BMP-12 and Ascorbic Acid Stimulation. The very presence of vitamin C in white blood cells, the fact that it supports the production of antibodies, supports and enhances the activities of several different types of white blood cells (NK cells, B cells, T cells, neutrophils, macrophages) all contribute to the inflammatory phase of wound healing, an essential and fundamental stage of the process. Vitamin C, also known as ascorbic acid, is an essential vitamin best know for its antioxidant and strong anti-inflammatory action, immune system enhancing effects and especially wound healing benefits. The National Institutes of Health’s list of roles Vitamin C plays is massive, and highlights how crucial the vitamin really is. There is no special diet that will heal your wound, but a healthy meal plan can help your wound heal faster. 4) In the remodeling phase, capillary growth finishes and the newly formed blood vessels regress to the point normal vascular density is achieved. Evaluation of the effect of ascorbic acid treatment on wound healing in mice exposed to different doses of fractionated gamma radiation. One of the original papers I found supporting Vitamin C and wound healing was a 1937 paper, so this is not news. Our cold press formulation makes sure your body gets the right amount of vitamin c it needs. A vitamin C deficiency is easily attainable, especially if there is no or poor access to fresh fruits and vegetables or supplementation. Kaplan B, Gönül B, Dinçer S, Dinçer Kaya FN, Babül A. Surg Today. Restor Dent Endod. 2) Physical illness: Anything from the common cold or flu to cardiovascular disease or cancer can use up the body’s entire vitamin C reserves and increase requirements. 2003 Mar;159(3):371-80. doi: 10.1667/0033-7587(2003)159[0371:eoteoa]2.0.co;2. The primary outcome was percent ulcer healing (reduction in ulcer size) at 8 weeks. By Ringsdorf WM Jr, Cheraskin E.. Good sources of vitamin C Vitamin C is found in a wide variety of fruit and vegetables. This is done with the help of human growth factors. 1 Month. 1982 Mar; 53(3):231-6. The major function of vitamin C (ascorbic acid) in wound healing is assisting in the formation of collagen, the most important protein of connective tissue. During the proliferative phase, AA contributes towards synthesis, maturation, secretion and degradation of collagen. 36 years experience in Geriatrics. Lymphocytes provide NK cells, T cells and B cells. It is needed for many functions in the body, including helping the body use carbohydrates, fats, and protein. Vitamins A, B, and C for Wound Healing Egg yolk is high in vitamin A, which promotes collagen synthesis and supports healthy wound healing. The stages of the wound healing process are: 1) Hemostasis: Stopping of bleeding by binding platelets or thrombocytes to form blood clots. Vitamin C or ascorbic acid (AA) is the antiscorbutic factor preventing scurvy. Encourage proper meal intake daily, including foods high in vitamin C content. In addition to getting proper rest and keeping the injured area clean, wound healing requires proper nutrition. Contact Us – Disclaimer Cookies Policy – Privacy Policy. How much vitamin C a day for wound healing benefits? Vitamin C, also known as ascorbic acid (AA), is involved in all phases of wound healing. Fifty percent of subjects had baseline vitamin C deficiency, half having undetectable levels. Collagen is synthesized to give strength and elasticity to the new skin tissue. Experimental study on humans. 2016 Feb;41(1):44-54. doi: 10.5395/rde.2016.41.1.44. 8) Oxidative stress caused by pollution, smoking, sun radiation and other factors. As a result of its immune system modulating action, vitamin C further reduces susceptibility to wound infection with subsequent benefits for skin tissue repair. Studies reveal that at a daily intake of 500 mg of vitamin C a day, blood plasma concentration reach an estimated 80 micromoles per liter, which is a desirable value for speeding the wound healing process. 6) Increased physical or mental effort. Vaxman F, Olender S, Lambert A, Nisand G, Grenier JF. 2) Sea buckthorn, rose hip, guava, blackcurrant, redcurrant, kiwifruit, papaya, strawberries, pineapple, cantaloupe, citrus fruit, mango, passion fruit. It increases the strength of the wound as it heals, and it helps with the creation of collagen in the skin. Dr. Fred Harvey answered. One of the most compelling reasons to recommend vitamin C is for skin health and chronic wound healing. In the inflammatory phase it is required for neutrophil apoptosis and clearance. Are Natural Ingredients Effective in the Management of Hyperpigmentation? Vitamin C is also vital to your body's healing process.An antioxidant, vitamin C might help protect your cells against the effects of free radicals — molecules produced when your body breaks down food or is exposed to tobacco smoke and radiation. Vitamin C. Vitamin C is an important antioxidant for wound healing. Ascorbic acid is essential for wound healing, but not the only required nutrient. The vitamin C dose for wound healing starts at 500 mg a day, with the average upper tolerable intake currently being set at 2,000 mg a day. It is essential for collagen synthesis, serving as cofactor in the enzymatic conversion of procollagen into collagen. 2004 Apr;17(3):109-12. doi: 10.1097/00129334-200404000-00010. – Effect of mega doses of vitamin C on bactericidal activity of leukocytes. Please enable it to take advantage of the complete set of features! 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